SS31 (Elamipretide)

Cardiolipin is a phospholipid found exclusively within the inner mitochondrial membrane and plays a central role in maintaining mitochondrial structure and function. It supports electron transport chain (ETC) supercomplex organization, facilitates electron transfer efficiency, and contributes to mitochondrial membrane architecture. Because cardiolipin integrity is closely linked to mitochondrial performance, SS-31’s selective interaction with cardiolipin makes it a valuable tool for studying mitochondrial bioenergetics, oxidative stress, and membrane dynamics.

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SS-31 is a mitochondria-targeted peptide that binds to cardiolipin in the inner mitochondrial membrane. It is widely studied for its effects on mitochondrial stability, oxidative stress, and cellular energy processes. Provided as a lyophilized powder, this compound is offered strictly for research use only.

  • High Purity – 99% Purity Guaranteed
  • Independently Lab Tested
  • Research Grade Quality
  • For Laboratory Research Use Only

SS-31 (Elamipretide; D-Arg-2′,6′-Dmt-Lys-Phe-NH2) is a synthetic mitochondria-targeted tetrapeptide that selectively binds cardiolipin, a phospholipid unique to the inner mitochondrial membrane. Through cardiolipin interaction, SS-31 supports electron transport chain (ETC) supercomplex stability, preserves mitochondrial membrane architecture, and promotes efficient electron transfer. Experimental studies have demonstrated reduced mitochondrial reactive oxygen species (ROS) generation, improved ATP production, and preservation of mitochondrial membrane potential under conditions of mitochondrial stress. Research applications include cardiolipin biology, mitochondrial bioenergetics, ETC supercomplex investigation, oxidative stress pathways, ROS signalling, mitochondrial membrane dynamics, and mitochondrial dysfunction research. Supplied as lyophilised preparation. Independently third-party HPLC-tested; COA available per batch.

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